Autoantibodies in Alzheimer’s disease:potential biomarkers,pathogenic roles,and therapeutic implications
摘要：Alzheimer’s disease(AD) is a prevalent and debilitating neurodegenerative disorder in the elderly.The etiology of AD has not been fully defined and currently there is no cure for this devastating disease.Compelling evidence suggests that the immune system plays a critical role in the pathophysiology of AD.Autoantibodies against a variety of molecules have been associated with AD.The roles of these autoantibodies in AD,however,are not well understood.This review attempts to summarize recent findings on these autoantibodies and explore their potential as diagnostic/prognostic biomarkers for AD,their roles in the pathogenesis of AD,and their implications in the development of effective immunotherapies for AD.
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南京醫科大學學報·自然科學版雜志
南京醫科大學學報·自然科學版雜志， 月刊，本刊重視學術導向，堅持科學性、學術性、先進性、創新性，刊載內容涉及的欄目：基礎研究、基礎醫學、綜述、病例報告、影像醫學、述評、公共衛生與預防醫學研究、影像醫學研究、病毒肺炎研究、公共衛生與預防醫學、預防醫學、口腔醫學研究、技術方法等。于1956年經新聞總署批準的正規刊物。
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