Journal Title：Structure

Structure aims to publish papers of exceptional interest in the field of structural biology. The journal strives to be essential reading for structural biologists, as well as biologists and biochemists that are interested in macromolecular structure and function. Structure strongly encourages the submission of manuscripts that present structural and molecular insights into biological function and mechanism. Other reports that address fundamental questions in structural biology, such as structure-based examinations of protein evolution, folding, and/or design, will also be considered. We will consider the application of any method, experimental or computational, at high or low resolution, to conduct structural investigations, as long as the method is appropriate for the biological, functional, and mechanistic question(s) being addressed. Likewise, reports describing single-molecule analysis of biological mechanisms are welcome.

In general, the editors encourage submission of experimental structural studies that are enriched by an analysis of structure-activity relationships and will not consider studies that solely report structural information unless the structure or analysis is of exceptional and broad interest. Studies reporting only homology models, de novo models, or molecular dynamics simulations are also discouraged unless the models are informed by or validated by novel experimental data; rationalization of a large body of existing experimental evidence and making testable predictions based on a model or simulation is often not considered sufficient.

《Structure》旨在發表結構生物學領域中特別受關注的論文。該期刊致力于成為結構生物學家以及對大分子結構和功能感興趣的生物學家和生物化學家的必讀讀物。《Structure》強烈鼓勵提交能夠展示生物功能和機制的結構和分子見解的稿件。其他涉及結構生物學基本問題（例如基于結構的蛋白質進化、折疊和/或設計檢查）的報告也將被考慮。我們將考慮應用任何方法（無論是實驗方法還是計算方法，高分辨率或低分辨率）進行結構研究，只要該方法適用于正在解決的生物學、功能和機制問題。同樣，也歡迎描述生物機制單分子分析的報告。

一般而言，編輯鼓勵提交通過結構-活性關系分析而豐富的實驗結構研究，并且不會考慮僅報告結構信息的研究，除非結構或分析具有特別和廣泛的興趣。不鼓勵僅報告同源模型、從頭模型或分子動力學模擬的研究，除非這些模型由新的實驗數據提供或驗證；對大量現有實驗證據進行合理化以及基于模型或模擬做出可測試的預測通常被認為是不夠的。

Structure創刊于1993年，由Cell Press出版商出版，收稿方向涵蓋生物 - 生化與分子生物學全領域，此刊是該細分領域中屬于非常不錯的SCI期刊，在行業細分領域中學術影響力較大，專業度認可很高，所以對原創文章要求創新性較高，如果您的文章質量很高，可以嘗試。平均審稿速度 一般,3-8周 ，影響因子指數4.4，該期刊近期沒有被列入國際期刊預警名單，廣大學者值得一試。